Self-Study Module 1 - CRSwNP: Providing Systemic Management and Optimizing Outcomes

Launch Date:
January 18, 2022
Expiration Date:
The accreditation for this activity has expired.
This brief publication discusses immune responses and therapeutic approaches in CRSwNP, including medical therapy, surgery, and targeted biologics. It features two brief videos that illuminate complex concepts on the mechanism of disease and the mechanism of action of biologics.

William Busse, MD

Emeritus Professor of Medicine
Division of Allergy, Pulmonary, and Critical Care Medicine
University of Wisconsin School of Medicine and Public Health
Madison, WI

William W. Busse, MD, is professor of medicine and member of the Division of Allergy, Pulmonary and Critical Care Medicine at the University of Wisconsin School of Medicine and Public Health in in Madison, WI, USA. 

After receiving his medical degree from the University of Wisconsin Medical School, Dr Busse served an internship at Cincinnati General Hospital in Cincinnati, OH. He subsequently went on to complete a residency in internal medicine and a fellowship in allergy and immunology at the University of Wisconsin. Dr. Busse is a Professor of Medicine in the Division of Allergy, Pulmonary and Critical Care Medicine at the University of Wisconsin School of Medicine and Public Health, Madison, WI

Dr Busse's chief research interests are mechanisms of asthma, including eosinophilic inflammation and rhinovirus-induced asthma, as well as asthmatic inflammation and neurocircuitry activation, for which he has had long-standing National Institutes of Health (NIH) support. He was principal investigator for the NIH’s National Institute of Allergy and Infectious Diseases Inner City Asthma Consortium to evaluate immune-based therapy for asthma in high risk urban children.

Over the years, Dr Busse has served on various national and international guidelines committees for the treatment of asthma, including the US National Asthma Education and Prevention Program (NAEPP) Guidelines for the Diagnosis and Management of Asthma, for which he was chair in 2007. He has been a member of the Advisory Council and Board of External Experts of the National Heart, Lung, and Blood Institute. Dr. Busse was president of the American Academy of Allergy and Immunology from 2000 to 2001. He has received numerous awards, including the American Thoracic Society Award for Scientific Accomplishments and the Breathing for Life Award. He has authored or coauthored more than 400 articles in peer-reviewed journals and served as coeditor of the textbooks Allergy: Principles and Practice and Asthma and Rhinitis.
 

Christine Franzese, MD

Professor of Clinical Otolaryngology
Director of Allergy
University of Missouri School of Medicine
Columbia, MO

Christine Franzese, MD is a general otolaryngologist, with a specialty focus on Allergy and Sinus Diseases, and Professor in the Department of Otolaryngology at University of Missouri Medical Center. She is a native of Watkins Glen, NY and received her undergraduate degree from Cornell University in Ithaca, NY. She received her M.D. from SUNY Upstate Medical Center and completed her residency training at Penn State Milton S. Hershey Medical Center and the University of Mississippi Medical Center. She stayed on as faculty at the University of Mississippi Medical Center for eight years where she was Residency Program Director, as well as Associate Professor and Chief of Otolaryngology at the G.V. “Sonny” Montgomery V.A. Medical Center.

 

She is a former Past President of the American Academy of Otolaryngic Allergy [AAOA]. Prior to that, she was President, President-Elect, and Treasurer of the AAOA, and Chair for the Section of Women in Otolaryngology in the American Academy of Otolaryngology-Head and Neck Surgery [AAO-HNS]. She has also served on the AAO-HNS Annual Program Committee and as Consultant to the AAO-HNS Allergy and Immunology Committee. She has taught at many allergy courses, including the AAOA Basic Allergy and Immunology Course, the AAOA Advanced Allergy and Immunology Course, and was co-Course Director for the AAOA Interactive Allergy & Rhinology Course. She has served as the first Chair of the SUO-Otolaryngology Program Directors Organization, as a member of the AAO-HNS Rhinology and Paranasal Sinuses Committee, and as a Member-at-Large on the AAOA Board of Directors. She has authored many scientific papers and is Chief Editor and one of the authors of “The Handbook of Otolaryngic Allergy” published in 2019. She has a special focus on biologics and treating allergic disorders, including inhalant allergy, penicillin allergy, allergies to stinging insects, food allergy, asthma, atopic dermatitis and urticaria.

1.
Discuss the disease burden of CRSwNP and its potential effects on patient quality of life
2.
Identify the common underlying pathophysiological mechanisms involved in CRSwNP and the spectrum of inflammatory diseases
3.
Adopt an individualized, interdisciplinary treatment approach for CRSwNP that incorporates current treatment modalities and optimizes outcomes